Influence of Antipruritics on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin.

NACompletedINTERVENTIONAL
Enrollment

13

Participants

Timeline

Start Date

June 11, 2019

Primary Completion Date

September 23, 2019

Study Completion Date

September 23, 2019

Conditions
Pruritus
Interventions
DRUG

Desloratadine 5 mg

Desloratadine (H1-antihistamine): oral tablet (1 x 5 mg), taken with 240 ml water, 4 hours prior to the histamine skin prick

DRUG

Aprepitant 125 mg

Aprepitant (NK1-antagonist): hard capsule (1 x 125 mg), taken with 240 ml water, 4 hours prior to the histamine skin prick

DRUG

Ketotifen 1 MG

Ketotifen (H1-antihistamine and mast cell stabilizer): capsule (1 x 1 mg), taken with 240 ml water, 4 hours prior to the histamine skin prick

Trial Locations (1)

3000

Center for Clinical Pharmacology, Leuven

All Listed Sponsors
lead

Universitaire Ziekenhuizen KU Leuven

OTHER

NCT04399148 - Influence of Antipruritics on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin. | Biotech Hunter | Biotech Hunter