Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma

Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York

NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York

NYP/Weill Cornell Medical Center, New York

Good Samaritan University Hospital, West Islip

State University of New York Upstate Medical University, Syracuse

University of Rochester, Rochester

Wexford Health and Wellness Pavilion, Wexford

Forbes Hospital, Monroeville

Allegheny General Hospital, Pittsburgh

University of Pittsburgh Cancer Institute (UPCI), Pittsburgh

UPMC-Shadyside Hospital, Pittsburgh

Lancaster General Ann B Barshinger Cancer Institute, Lancaster

Lancaster General Hospital, Lancaster

Lehigh Valley Hospital-Cedar Crest, Allentown

Crozer-Keystone Regional Cancer Center at Broomall, Broomall

Thomas Jefferson University Hospital, Philadelphia

Christiana Care Health System-Concord Health Center, Chadds Ford

Reading Hospital, West Reading

Delaware Clinical and Laboratory Physicians PA, Newark

Helen F Graham Cancer Center, Newark

Medical Oncology Hematology Consultants PA, Newark

Christiana Care Health System-Christiana Hospital, Newark

Beebe Medical Center, Lewes

Beebe South Coastal Health Campus, Millville

Beebe Health Campus, Rehoboth Beach

UM Upper Chesapeake Medical Center, Bel Air

Central Maryland Radiation Oncology in Howard County, Columbia

UM Baltimore Washington Medical Center/Tate Cancer Center, Glen Burnie

University of Maryland/Greenebaum Cancer Center, Baltimore

Inova Schar Cancer Institute, Fairfax

VCU Massey Comprehensive Cancer Center, Richmond

VCU Community Memorial Health Center, South Hill

Wheeling Hospital/Schiffler Cancer Center, Wheeling

Atrium Health Cabarrus/LCI-Concord, Concord

Carolinas Medical Center/Levine Cancer Institute, Charlotte

Atrium Health Pineville/LCI-Pineville, Charlotte

Rock Hill Radiation Therapy Center, Rock Hill

Augusta University Medical Center, Augusta

Memorial Health University Medical Center, Savannah

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler, Savannah

Lewis Hall Singletary Oncology Center, Thomasville

Baptist MD Anderson Cancer Center, Jacksonville

AdventHealth Orlando, Orlando

University of Alabama at Birmingham Cancer Center, Birmingham

Baptist Memorial Hospital and Cancer Center-Collierville, Collierville

Baptist Memorial Hospital and Cancer Center-Memphis, Memphis

Baptist Memorial Hospital and Cancer Center-Desoto, Southhaven

University of Mississippi Medical Center, Jackson

University of Kentucky/Markey Cancer Center, Lexington

Dublin Methodist Hospital, Dublin

Riverside Methodist Hospital, Columbus

Case Western Reserve University, Cleveland

Cleveland Clinic Foundation, Cleveland

Summa Health System - Akron Campus, Akron

Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis

IU Health Methodist Hospital, Indianapolis

Corewell Health William Beaumont University Hospital, Royal Oak

Corewell Health Beaumont Troy Hospital, Troy

Henry Ford Health Warren Hospital, Warren

Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor

Trinity Health IHA Medical Group Hematology Oncology - Brighton, Brighton

Trinity Health Medical Center - Brighton, Brighton

Chelsea Hospital, Chelsea

Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital, Chelsea

Corewell Health Dearborn Hospital, Dearborn

Trinity Health Saint Mary Mercy Livonia Hospital, Livonia

Trinity Health IHA Medical Group Hematology Oncology - Canton, Canton

Trinity Health Medical Center - Canton, Canton

Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti

Henry Ford Health Saint John Hospital, Detroit

Michigan Healthcare Professionals Pontiac, Pontiac

Genesys Hurley Cancer Institute, Flint

Hurley Medical Center, Flint

MyMichigan Medical Center Saginaw, Saginaw

Oncology Hematology Associates of Saginaw Valley PC, Saginaw

Saint Mary's Oncology/Hematology Associates of West Branch, West Branch

MyMichigan Medical Center Tawas, Tawas City

Bronson Methodist Hospital, Kalamazoo

West Michigan Cancer Center, Kalamazoo

Beacon Kalamazoo, Kalamazoo

Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids

University of Michigan Health - West, Wyoming

Mary Greeley Medical Center, Ames

McFarland Clinic - Ames, Ames

Mercy Medical Center-West Lakes, West Des Moines

Iowa Methodist Medical Center, Des Moines

UI Health Care Mission Cancer and Blood - Des Moines Clinic, Des Moines

Broadlawns Medical Center, Des Moines

Mercy Medical Center - Des Moines, Des Moines

UI Health Care Mission Cancer and Blood - Laurel Clinic, Des Moines

Mercy Cancer Center-West Lakes, Clive

UI Health Care Mission Cancer and Blood - West Des Moines Clinic, Clive

Greater Regional Medical Center, Creston

Heartland Oncology and Hematology LLP, Council Bluffs

Methodist Jennie Edmundson Hospital, Council Bluffs

University of Iowa/Holden Comprehensive Cancer Center, Iowa City

Aurora Health Care Germantown Health Center, Germantown

Aurora Cancer Care-Grafton, Grafton

University of Wisconsin Carbone Cancer Center - Johnson Creek, Johnson Creek

Aurora Medical Center in Summit, Summit

Vince Lombardi Cancer Clinic-Sheboygan, Sheboygan

Aurora Cancer Care-Southern Lakes VLCC, Burlington

Aurora Cancer Care-Kenosha South, Kenosha

Aurora Cancer Care-Milwaukee, Milwaukee

Aurora Saint Luke's Medical Center, Milwaukee

Aurora Cancer Care-Milwaukee West, Wauwatosa

Aurora West Allis Medical Center, West Allis

Aurora Sinai Medical Center, Milwaukee

Aurora Cancer Care-Racine, Racine

University of Wisconsin Carbone Cancer Center - University Hospital, Madison

Cancer Center of Western Wisconsin, New Richmond

Aurora Bay Area Medical Group-Marinette, Marinette

Vince Lombardi Cancer Clinic-Two Rivers, Two Rivers

Aurora BayCare Medical Center, Green Bay

Marshfield Medical Center - Minocqua, Minocqua

Vince Lombardi Cancer Clinic - Oshkosh, Oshkosh

Lakeview Hospital, Stillwater

Regions Hospital, Saint Paul

United Hospital, Saint Paul

Minnesota Oncology Hematology PA-Maplewood, Maplewood

Fairview Ridges Hospital, Burnsville

Minnesota Oncology - Burnsville, Burnsville

Fairview Clinics and Surgery Center Maple Grove, Maple Grove

Hennepin County Medical Center, Minneapolis

Park Nicollet Clinic - Saint Louis Park, Saint Louis Park

Unity Hospital, Fridley

Mercy Hospital, Coon Rapids

Fairview Southdale Hospital, Edina

Health Partners Inc, Minneapolis

Sanford Joe Lueken Cancer Center, Bemidji

Sanford Cancer Center Oncology Clinic, Sioux Falls

Avera Cancer Institute, Sioux Falls

Avera Cancer Institute at Pierre, Pierre

Sanford Broadway Medical Center, Fargo

Sanford Roger Maris Cancer Center, Fargo

Sanford Bismarck Medical Center, Bismarck

Billings Clinic Cancer Center, Billings

Benefis Sletten Cancer Institute, Great Falls

Saint James Community Hospital and Cancer Treatment Center, Butte

Bozeman Health Deaconess Hospital, Bozeman

Logan Health Medical Center, Kalispell

NorthShore University HealthSystem-Glenbrook Hospital, Glenview

NorthShore University HealthSystem-Highland Park Hospital, Highland Park

Advocate Lutheran General Hospital, Park Ridge

Northwestern Medicine Cancer Center Kishwaukee, DeKalb

Elmhurst Memorial Hospital, Elmhurst

Northwestern Medicine Cancer Center Delnor, Geneva

NorthShore University HealthSystem-Evanston Hospital, Evanston

Edward Hospital/Cancer Center, Naperville

Northwestern Medicine Cancer Center Warrenville, Warrenville

Northwestern University, Chicago

University of Illinois, Chicago

UW Health Carbone Cancer Center Rockford, Rockford

Illinois CancerCare-Ottawa Clinic, Ottawa

Illinois CancerCare-Peru, Peru

Illinois CancerCare-Princeton, Princeton

Illinois CancerCare-Galesburg, Galesburg

Western Illinois Cancer Treatment Center, Galesburg

Illinois CancerCare-Kewanee Clinic, Kewanee

Illinois CancerCare-Macomb, Macomb

Illinois CancerCare-Canton, Canton

Illinois CancerCare-Eureka, Eureka

Illinois CancerCare-Pekin, Pekin

Illinois CancerCare - Washington, Washington

Illinois CancerCare-Peoria, Peoria

Methodist Medical Center of Illinois, Peoria

OSF Saint Francis Medical Center, Peoria

Illinois CancerCare-Bloomington, Bloomington

Carle Cancer Center, Urbana

The Carle Foundation Hospital, Urbana

Carle at The Riverfront, Danville

Carle Physician Group-Mattoon/Charleston, Mattoon

Cancer Care Center of O'Fallon, O'Fallon

Illinois CancerCare-Carthage, Carthage

Carle Physician Group-Effingham, Effingham

Crossroads Cancer Center, Effingham

Cancer Care Specialists of Illinois - Decatur, Decatur

Decatur Memorial Hospital, Decatur

Southern Illinois University School of Medicine, Springfield

Springfield Clinic, Springfield

Springfield Memorial Hospital, Springfield

Centralia Oncology Clinic, Centralia

Saint Francis Medical Center, Cape Girardeau

Nebraska Methodist Hospital, Omaha

Nebraska Medicine-Village Pointe, Omaha

Nebraska Medicine-Bellevue, Bellevue

University of Nebraska Medical Center, Omaha

Cancer Partners of Nebraska, Lincoln

Tulane University School of Medicine, New Orleans

Ochsner Medical Center Jefferson, New Orleans

University of Arkansas for Medical Sciences, Little Rock

University of Oklahoma Health Sciences Center, Oklahoma City

Cancer Centers of Southwest Oklahoma Research, Lawton

Memorial Hermann Texas Medical Center, Houston

University of Texas Health Science Center at San Antonio, San Antonio

AdventHealth Littleton, Littleton

AdventHealth Parker, Parker

AdventHealth Porter, Denver

Penrose-Saint Francis Healthcare, Colorado Springs

Saint Luke's Cancer Institute - Twin Falls, Twin Falls

Saint Alphonsus Cancer Care Center-Caldwell, Caldwell

Saint Luke's Cancer Institute - Fruitland, Fruitland

Saint Luke's Cancer Institute - Meridian, Meridian

Saint Alphonsus Cancer Care Center-Nampa, Nampa

Saint Luke's Cancer Institute - Nampa, Nampa

Saint Luke's Cancer Institute - Boise, Boise

American Fork Hospital / Huntsman Intermountain Cancer Center, American Fork

Riverton Hospital, Riverton

Intermountain Medical Center, Murray

Huntsman Cancer Institute/University of Utah, Salt Lake City

LDS Hospital, Salt Lake City

Logan Regional Hospital, Logan

McKay-Dee Hospital Center, Ogden

Utah Valley Regional Medical Center, Provo

Sandra L Maxwell Cancer Center, Cedar City

Saint George Regional Medical Center, St. George

Kaiser Permanente Los Angeles Medical Center, Los Angeles

Cedars Sinai Medical Center, Los Angeles

Torrance Memorial Physician Network - Cancer Care, Torrance

Torrance Memorial Medical Center, Torrance

Kaiser Permanente-Ontario, Ontario

UC San Diego Moores Cancer Center, La Jolla

Loma Linda University Medical Center, Loma Linda

Kaiser Permanente-Anaheim, Anaheim

UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange

John Muir Medical Center-Concord, Concord

John Muir Medical Center-Walnut Creek, Walnut Creek

Sutter Auburn Faith Hospital, Auburn

Sutter Cancer Centers Radiation Oncology Services-Auburn, Auburn

Sutter Cancer Centers Radiation Oncology Services-Roseville, Roseville

Sutter Roseville Medical Center, Roseville

Sutter Medical Center Sacramento, Sacramento

University of California Davis Comprehensive Cancer Center, Sacramento

Hawaii Cancer Care - Westridge, ‘Aiea

Pali Momi Medical Center, ‘Aiea

Queen's Cancer Center - Pearlridge, ‘Aiea

The Cancer Center of Hawaii-Pali Momi, ‘Aiea

Castle Medical Center, Kailua

Wilcox Memorial Hospital and Kauai Medical Clinic, Lihue

Hawaii Cancer Care Inc - Waterfront Plaza, Honolulu

Island Urology, Honolulu

Queen's Cancer Cenrer - POB I, Honolulu

Queen's Medical Center, Honolulu

Straub Clinic and Hospital, Honolulu

University of Hawaii Cancer Center, Honolulu

Hawaii Cancer Care Inc-Liliha, Honolulu

Queen's Cancer Center - Kuakini, Honolulu

The Cancer Center of Hawaii-Liliha, Honolulu

Kapiolani Medical Center for Women and Children, Honolulu

Clackamas Radiation Oncology Center, Clackamas

Providence Cancer Institute Clackamas Clinic, Clackamas

Legacy Mount Hood Medical Center, Gresham

Legacy Meridian Park Hospital, Tualatin

Providence Newberg Medical Center, Newberg

Legacy Good Samaritan Hospital and Medical Center, Portland

Providence Portland Medical Center, Portland

Providence Saint Vincent Medical Center, Portland

Kaiser Permanente Northwest, Portland

Virginia Mason Medical Center, Seattle

Legacy Cancer Institute Medical Oncology and Day Treatment, Vancouver

Legacy Salmon Creek Hospital, Vancouver

Hartford Hospital, Hartford

The Hospital of Central Connecticut, New Britain

Eastern Maine Medical Center, Bangor

MaineHealth Coastal Cancer Treatment Center, Bath

MaineHealth Waldo Hospital, Belfast

Lafayette Family Cancer Center-EMMC, Brewer

MaineHealth Maine Medical Center - Portland, Portland

Penobscot Bay Medical Center, Rockport

MaineHealth Cancer Care Center of York County, Sanford

Maine Medical Partners Neurology, Scarborough

MaineHealth Maine Medical Center- Scarborough, Scarborough

MaineHealth Cancer Care and IV Therapy - South Portland, South Portland

Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon

Hackensack University Medical Center, Hackensack

Saint Barnabas Medical Center, Livingston

Morristown Medical Center, Morristown

Jersey Shore Medical Center, Neptune City

Rutgers Cancer Institute of New Jersey, New Brunswick

Capital Health Medical Center-Hopewell, Pennington

Overlook Hospital, Summit

Sanford USD Medical Center - Sioux Falls, Sioux Falls

Central Vermont Medical Center/National Life Cancer Treatment, Berlin Corners

University of Vermont Medical Center, Burlington

University of Vermont and State Agricultural College, Burlington