A Study of CC-98633, BCMA-targeted Chimeric Antigen Receptor (CAR) T Cells, in Participants With Relapsed and/or Refractory Multiple Myeloma

PHASE1CompletedINTERVENTIONAL
Enrollment

78

Participants

Timeline

Start Date

August 18, 2020

Primary Completion Date

July 3, 2024

Study Completion Date

July 3, 2024

Conditions
Multiple Myeloma
Interventions
BIOLOGICAL

CC-98633

"Subjects will undergo leukapheresis to isolate peripheral blood mononuclear cells (PBMCs) to produce CC-98633.~During CC-98633 production, subjects may receive bridging chemotherapy for disease control. Upon successful generation of CC-98633 product, subjects will receive treatment with CC-98633 therapy.~Study treatment will include lymphodepleting chemotherapy followed by one dose of CC-98633 administered by intravenous (IV) injection."

Trial Locations (11)

10029

Local Institution - 104, New York

10065

Local Institution - 102, New York

14263

Local Institution - 106, Buffalo

28204

Local Institution - 108, Charlotte

35233

Local Institution - 103, Birmingham

55905

Local Institution - 109, Rochester

60637

Local Institution - 107, Chicago

75390

Local Institution - 105, Dallas

85054

Local Institution - 111, Phoenix

94305

Local Institution - 110, Stanford

66205-2003

Local Institution - 101, Westwood

All Listed Sponsors
lead

Juno Therapeutics, a Subsidiary of Celgene

INDUSTRY

NCT04394650 - A Study of CC-98633, BCMA-targeted Chimeric Antigen Receptor (CAR) T Cells, in Participants With Relapsed and/or Refractory Multiple Myeloma | Biotech Hunter | Biotech Hunter