A Study to Assess the Safety, Pharmacokinetics and Anti Tumor Activity of UCB6114 Administered Intravenously to Participants With Advanced Solid Tumors

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

93

Participants

Timeline

Start Date

July 9, 2020

Primary Completion Date

April 11, 2024

Study Completion Date

April 11, 2024

Conditions
Advanced Solid Tumors
Interventions
DRUG

ginisortamab

Study participants will receive predefined doses of ginisortamab (UCB6114) administered intravenously at pre-specified time points.

DRUG

trifluridine/tipiracil

Study participants will receive predefined doses of trifluridine/tipiracil (TFD/TPI) administered as film-coated tablets at pre-specified time points.

DRUG

mFOLFOX6

Study participants will receive predefined doses of oxaliplatin, Leucovorin and 5-fluorouracil as part of the mFOLFOX6 chemotherapy regimen administered as intravenous (iv) infusion at prespecified time points.

Trial Locations (9)

29425

Onc001 50470, Charleston

77030

Onc001 50471, Houston

90033

Onc001 50414, Los Angeles

Unknown

Onc001 40305, Glasgow

Onc001 40113, London

Onc001 40304, Manchester

Onc001 40306, Newcastle upon Tyne

Onc001 40303, Oxford

Onc001 40302, Sutton

All Listed Sponsors
lead

UCB Biopharma SRL

INDUSTRY

NCT04393298 - A Study to Assess the Safety, Pharmacokinetics and Anti Tumor Activity of UCB6114 Administered Intravenously to Participants With Advanced Solid Tumors | Biotech Hunter | Biotech Hunter