Wound Infiltration With Tramadol, Dexmedetomidine, or Magnesium Plus Ropivacaine for Pain Relief After Spine Surgery

PHASE4CompletedINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

May 10, 2020

Primary Completion Date

November 8, 2022

Study Completion Date

December 10, 2022

Conditions
AnalgesiaPain, PostoperativeSpinal StenosisSpinal Disease
Interventions
DRUG

Tramadol with ropivacaine

A solution of tramadol 2mg/kg with ropivacaine hydrochloride (10mg/ml) 100mg mixture making up a total volume of 15ml will be infiltrated in the surgical trauma area before closure.

DRUG

Dexmedetomidine with ropivacaine

A solution of dexmedetomidine 1μg/kg with ropivacaine hydrochloride (10mg/ml) 100mg mixture making up a total volume of 15ml will be infiltrated in the surgical trauma area before closure.

DRUG

Magnesium with ropivacaine

A solution of magnesium 10 mg/kg with ropivacaine hydrochloride (10mg/ml) 100mg mixture making up a total volume of 15ml will be infiltrated in the surgical trauma area before closure.

DRUG

Ropivacaine plus normal saline

A solution of ropivacaine hydrochloride (10mg/ml) 100mg with 5ml of isotonic saline 0.9% mixture making up a total volume of 15ml will be infiltrated in the surgical trauma area before closure.

Trial Locations (1)

54636

AHEPA University Hospital, Thessaloniki

All Listed Sponsors
lead

Aristotle University Of Thessaloniki

OTHER

NCT04391855 - Wound Infiltration With Tramadol, Dexmedetomidine, or Magnesium Plus Ropivacaine for Pain Relief After Spine Surgery | Biotech Hunter | Biotech Hunter