Mini-PNCL vs fURS in Management of Nephrolithiasis

NACompletedINTERVENTIONAL
Enrollment

76

Participants

Timeline

Start Date

October 5, 2020

Primary Completion Date

April 24, 2024

Study Completion Date

April 24, 2024

Conditions
NephrolithiasisKidney Stone
Interventions
PROCEDURE

Flexible ureteroscopy

Retograde intrarenal surgery (RIRS) has gained much popularity especially when the role of SWL, in management of LPS, has been significantly diminished in the few last years5. RIRS is dependent mainly on flexible ureteroscopy (fURS). fURS increases the quality and performance of upper urinary tract exploration, allowing for the treatment of the majority of stones at all sites. Moreover, it is associated with no risk of renal parenchymal injuries and a very low risk of bleeding.

PROCEDURE

Mini-percutaneous nephrolithotomy

PCNL has regained popularity thanks to the possibility of using reduced calibers and modern technology, which has reduced the complications without compromising the stone clearance, and more efficient intracorporeal lithotripter modalities. However, PCNL is still a challenging surgical technique and can be associated with significant complications that may compromise its efficacy. In the present time, we have available calibers ranging from 4.8 to 30 French. Many reports advocate that morbidity after PCNL may be reduced by recent modifications, such as mini-PCNL (miniperc). One meta-analysis of mini-PCNL and conventional PCNL demonstrated that mini-PCNL had a greater safety profile with similar stone free rates (SFRs).

Trial Locations (1)

P7B6V4

Thunder Bay Regional Health Sciences Centre/Thunder Bay Regional Health Research Institute, Thunder Bay

All Listed Sponsors
lead

Thunder Bay Regional Health Research Institute

OTHER

NCT04389853 - Mini-PNCL vs fURS in Management of Nephrolithiasis | Biotech Hunter | Biotech Hunter