To Evaluate the Efficacy and Feasibility of Modified Reduce-volume Target IMRT in the Treatment of Patients With Non-metastatic NPC

CompletedOBSERVATIONAL
Enrollment

471

Participants

Timeline

Start Date

June 1, 2020

Primary Completion Date

August 1, 2020

Study Completion Date

October 1, 2020

Conditions
Nasopharyngeal Carcinoma
Interventions
RADIATION

modified reduce-volume target IMRT

The gross tumor volume of the nasopharynx and neck nodes (GTVnx and GTVnd) were delineated according to the tumor extension. The CTVnx was defined as GTVnx + nasopharynx mucosa + 8mm +corresponding anatomical structure without the delineation of CTV1. The CTVnd was defined as GTVnd plus the elective neck area. The prescribe doses of GTVnx/GTVnd, CTVnx, CTVnd were 66-70Gy,54-56Gy and 50-54Gy in 31-35 fractions, respectively.

Trial Locations (1)

350014

Department of radiation oncology, Fujian cancer hospital, Fuzhou

All Listed Sponsors
lead

Fujian Cancer Hospital

OTHER_GOV

NCT04387266 - To Evaluate the Efficacy and Feasibility of Modified Reduce-volume Target IMRT in the Treatment of Patients With Non-metastatic NPC | Biotech Hunter | Biotech Hunter