Haemophilia and Bone Loss - PHILEOS Study

NARecruitingINTERVENTIONAL
Enrollment

480

Participants

Timeline

Start Date

June 2, 2020

Primary Completion Date

March 31, 2025

Study Completion Date

March 31, 2025

Conditions
Hemophilia
Interventions
RADIATION

Bone densitometry (BMD)

"Recruitment of haemophilic patients during a routine visit at the haemophilia centre.~Information of the subjects that the study requires a BMD measure for all and a blood sampling for patients only.~After inclusion and exclusion criteria have been checked, the subject can sign the consent.~For all subjects, an appointment will be made for BMD measure.~For patients and controls: BMD will be measured by Dual Energy X-ray Absorptiometry (DXA) technology, on femoral and lumbar spine (L2-L4) sites.~Recruitment of healthy volunteers through registers (Clinical Investigation Centers) and advertisements."

BIOLOGICAL

Blood sampling for patients only

For patients, fVIII/fIX activity and antigen, thrombin generation potential and plasmatic markers of bone remodelling will be measured centrally.

Trial Locations (23)

1134

COMPLETED

MHEK, Budapest

10000

COMPLETED

University Hospital Centre Zagreb, Zagreb

13010

RECRUITING

Chu La Timone Marseille, Marseille

21000

RECRUITING

Chu de Dijon, Dijon

29200

RECRUITING

Chu Brest Hopital Morvan, Brest

33076

RECRUITING

Chu de Bordeaux, Bordeaux

34295

RECRUITING

CHU - Saint Eloi, Montpellier

35000

RECRUITING

Chu Rennes Hopital Pontchaillou, Rennes

38700

RECRUITING

Chu Grenoble Alpes, Grenoble

42055

RECRUITING

CHU de Saint-Etienne, Saint-Etienne

73000

RECRUITING

Centre Hospitalier Metropole Savoie, Chambéry

75015

RECRUITING

Chu Necker Paris, Paris

Unknown

RECRUITING

BELGIUM - Brussels, Brussels

RECRUITING

HCL - Groupement Hospitalier Est (Hôpital Louis Pradel), Bron

RECRUITING

CHU Caen, Caen

RECRUITING

Chu Cth Estaing Clermont Ferrand, Clermont-Ferrand

RECRUITING

CHU Lille, Lille

RECRUITING

CHU Nancy, Nancy

RECRUITING

CHU de Nantes, Nantes

RECRUITING

APHP - Bicêtre, Paris

RECRUITING

CHU de ROUEN, Rouen

RECRUITING

Chu Strasbourg - Hôpital de Hautepierre, Strasbourg

RECRUITING

ROMANIA - Bucharest, Bucharest

All Listed Sponsors
collaborator

Ministry of Health, France

OTHER_GOV

lead

Centre Hospitalier Universitaire de Saint Etienne

OTHER