Cocoa/Carob Polyphenols and Postprandial Changes in Type 2 Diabetes

NACompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

May 3, 2021

Primary Completion Date

February 28, 2022

Study Completion Date

July 30, 2023

Conditions
Type 2 Diabetes
Interventions
OTHER

No product (A)/mixture of coca and carob together with breakfast (B)/mixture of coca and carob 10 h before breakfast (C)

The subjects will receive, after overnight fasting, a high-fat high-sugar breakfast. In treatment A, they will not receive any additional product; in treatment B, they will receive at the same time a mixture of coca and carob; in treatment C, they will receive the mixture of coca and carob 10 h before breakfast. A total of 6 blood samples will be collected during each visit: 0-30-60-120-180-240-270 min. Urine samples will be collected during the permanence of the subjects in the Unit of Human Nutrition. Feces will be collected the first time they are generated after treatments A and C. Both interventions will be separated by two weeks. Subjects will be instructed not to modify their dietary habits during the development of the study, but during the 72 h before each visit they will have to restrict the intake of polyphenol-rich foods (a detailed list will be provided).

Trial Locations (1)

28040

Institute of Food Science, Technology and Nutrition, National Research Council (ICTAN-CSIC), Madrid

All Listed Sponsors
collaborator

Ministerio de Economía y Competitividad, Spain

OTHER_GOV

lead

National Research Council, Spain

OTHER_GOV