Effect of Hydration Guided by Vigileo on the Prevention of CIN After PCI for Patients With AMI

NACompletedINTERVENTIONAL
Enrollment

344

Participants

Timeline

Start Date

July 10, 2020

Primary Completion Date

May 30, 2022

Study Completion Date

December 21, 2022

Conditions
Myocardial InfarctionContrast-induced Nephropathy
Interventions
PROCEDURE

the adequate hydration group guided by Vigileo

If the patient is mechanically ventilated, the following scheme is adopted: if SVV≤10%, then adjust the rehydration speed to 1 ml/kg/h; if 10%\<SVV\<15%, then adjust the rehydration speed to 2 ml/kg/h; if SVV≥15%, then adjust the rehydration speed to 3 ml/kg/h. The hydration lasts 24 hours after operation, and the rehydration speed is changed according to the SVV. If the patient does not use mechanical ventilation, the following scheme is adopted: 250ml normal saline is administered within 10 minutes after direct PCI, and the rehydration volume changes to 125ml in patients with mild-to-moderate congestive heart failure. If the increment of SV≥15%, then adjust the rehydration speed to 3 ml/kg/h; if 10%≤the increment of SV\<15%, then adjust the rehydration speed to 2 ml/kg/h; if the increment of SV\<10%, then adjust the rehydration speed to 1 ml/kg/h. Reassessed every 1 hour until SV is stable,and the hydration also lasts 24 hours after operation.

Trial Locations (1)

100853

Chinese People's Liberation Army General Hospital, Beijing

All Listed Sponsors
collaborator

Lu jiang hospital

UNKNOWN

lead

Chinese PLA General Hospital

OTHER

NCT04382313 - Effect of Hydration Guided by Vigileo on the Prevention of CIN After PCI for Patients With AMI | Biotech Hunter | Biotech Hunter