A Study to Evaluate the Efficacy and Safety of Sirukumab in Confirmed Severe or Critical Confirmed Coronavirus Disease (COVID)-19

PHASE2CompletedINTERVENTIONAL
Enrollment

212

Participants

Timeline

Start Date

April 24, 2020

Primary Completion Date

April 9, 2021

Study Completion Date

June 24, 2021

Conditions
Critical Confirmed Coronavirus Disease (COVID)-19
Interventions
DRUG

Sirukumab

Participants will receive single dose infusion of sirukumab on Day 1.

DRUG

Placebo

Participants will receive placebo IV single dose infusion on Day 1.

OTHER

Standard of Care (SOC)

SOC treatment will be determined by the investigator based on local practice and consists of supportive care.

Trial Locations (16)

13210

SUNY Upstate Medical University, Syracuse

27834

East Carolina University, Greenville

33308

Holy Cross Hospital - Michael and Dianne Bienes Comprehensive Cancer Center, Fort Lauderdale

48073

Beaumont Health Systems, Royal Oak

48202

Henry Ford Hospital, Detroit

59701

Mercury Street Medical Group, PLLC, Butte

60153

Loyola University Medical Center, Maywood

60640

Great Lakes Clinical Trials, Chicago

61637

University of Illinois College of Medicine at Peoria, Peoria

63110

Washington University School of Medicine, St Louis

70012

Louisiana State University Health Sciences Center, New Orleans

75246

Baylor Scott & White Research Institute, Dallas

76104

Baylor All Saints Medical Center at Fort Worth, Fort Worth

90806

MemorialCare Research Miller Children's and Women's Hospital Long Beach, Long Beach

92663

Hoag Memorial Hospital, Newport Beach

07102

Saint Michaels Medical Center - Infectious Disease, Newark

All Listed Sponsors
lead

Janssen Pharmaceutica N.V., Belgium

INDUSTRY

NCT04380961 - A Study to Evaluate the Efficacy and Safety of Sirukumab in Confirmed Severe or Critical Confirmed Coronavirus Disease (COVID)-19 | Biotech Hunter | Biotech Hunter