Percutaneous Endoscopic Gastrostomy Before Definitive Concurrent Chemoradiation Therapy for Esophageal Squamous Cell Carcinoma

PHASE2CompletedINTERVENTIONAL
Enrollment

63

Participants

Timeline

Start Date

February 1, 2020

Primary Completion Date

March 15, 2022

Study Completion Date

March 15, 2022

Conditions
Esophageal Squamous Cell Carcinoma
Interventions
COMBINATION_PRODUCT

Concurrent chemoradiotherapy combined with enteral feeding by percutaneous endoscopic gastrostomy

"One or two weeks before CCRT, all patients will undergo a percutaneous endoscopic gastrostomy (PEG) to be administered enteral nutrition support(30-35 kcal/kg of energy, 1.2-1.5g/kg of protein and electrolyte supplementation each day). Nutritional supplements will be administered till 1 month after CCRT.~All patients will receive definitive radiotherapy combined with three cycles of S-1 (40mg/2, BID, po) on D1-14, D22-35, D43-56."

Trial Locations (1)

510000

Hui Liu, Guangzhou

All Listed Sponsors
lead

Sun Yat-sen University

OTHER

NCT04380480 - Percutaneous Endoscopic Gastrostomy Before Definitive Concurrent Chemoradiation Therapy for Esophageal Squamous Cell Carcinoma | Biotech Hunter | Biotech Hunter