Study Comparing Continuous Subcutaneous Infusion Of ABBV-951 With Oral Carbidopa/Levodopa Tablets For Treatment Of Motor Fluctuations In Adult Participants With Advanced Parkinson's Disease

PHASE3CompletedINTERVENTIONAL
Enrollment

174

Participants

Timeline

Start Date

October 19, 2020

Primary Completion Date

September 29, 2021

Study Completion Date

September 29, 2021

Conditions
Parkinson's Disease (PD)
Interventions
DRUG

ABBV-951

Solution for continuous subcutaneous infusion (CSCI)

DRUG

Placebo for Levodopa/Carbidopa (LD/CD)

Oral capsule

DRUG

Levodopa/Carbidopa (LD/CD)

Oral encapsulated tablet

DRUG

Placebo for ABBV-951

Solution for continuous subcutaneous infusion (CSCI)

Trial Locations (76)

2145

Westmead Hospital /ID# 216535, Westmead

2170

Liverpool Hospital /ID# 218681, Liverpool

3050

The Royal Melbourne Hospital /ID# 216536, Parkville

3192

Kingston Centre /ID# 216537, Cheltenham

4215

Gold coast University Hospital /ID# 218373, Southport

5000

Royal Adelaide Hospital /ID# 216533, Adelaide

10003

Mount Sinai Beth Israel /ID# 216712, New York

11042

Northwell Health /ID# 216833, Lake Success

19107

Thomas Jefferson University Hospital /ID# 216553, Philadelphia

19713

Christiana Care Health Service /ID# 216515, Newark

20007

Georgetown University Hospital /ID# 216632, Washington D.C.

27157

Wake Forest Univ HS /ID# 216522, Winston-Salem

29615

Prisma Health-Upstate /ID# 216594, Greenville

29650

Premier Neurology, P.C. /ID# 217308, Greer

30331

Duplicate_Atlanta Center for Medical Res /ID# 217091, Atlanta

30501

The Neurological Center of North Georgia /ID# 216499, Gainesville

32174

Neurology Associates Ormond Beach /ID# 216521, Ormond Beach

33445

Brain Matters Research /ID# 217089, Delray Beach

33486

Parkinson's Disease and Movement Disorders Center of Boca Raton /ID# 216517, Boca Raton

33612

University of South Florida /ID# 216638, Tampa

33980

Parkinson's Disease Treatment Center of Southwest Florida /ID# 222656, Port Charlotte

34470

Renstar Medical Research /ID# 216765, Ocala

35233

University of Alabama at Birmingham - Main /ID# 216595, Birmingham

46202

Indiana Clinical Research Cent /ID# 216615, Indianapolis

48824

Michigan State University /ID# 217158, East Lansing

60612

Rush University Medical Center /ID# 216567, Chicago

60637

University of Chicago Medical /ID# 217187, Chicago

63110

Washington University-School of Medicine /ID# 216548, St Louis

64111

St. Luke's Hosp. of Kansas City /ID# 216633, Kansas City

66160

Univ Kansas Med Ctr /ID# 216528, Kansas City

72205

University of Arkansas for Medical Sciences /ID# 216501, Little Rock

77030

Houston Methodist Hospital /ID# 216707, Houston

77429

Houston Pulmonary Sleep and Allergy Associates /ID# 216942, Cypress

78681

Central Texas Neurology Consul /ID# 216629, Round Rock

80045

University of Colorado Hospital /ID# 216527, Aurora

84132

University of Utah Health Care /ID# 216710, Salt Lake City

85004

Xenoscience, Inc /ID# 217110, Phoenix

85351

Banner Sun Health Res Inst /ID# 216507, Sun City

90048

Cedars-Sinai Medical Center-West Hollywood /ID# 216561, West Hollywood

90095

University of California, Los Angeles /ID# 216674, Los Angeles

90806

Collaborative Neuroscience Research - Long Beach /ID# 216970, Long Beach

92093

University of California, San /ID# 216598, La Jolla

92354

Loma Linda University Medical /ID# 216500, Loma Linda

92708

The Parkinson's & Movement Disorder Institute - Fountain Valley /ID# 216705, Fountain Valley

36604-3302

University of South Alabama /ID# 216757, Mobile

85013-4407

Barrow Neurological Institute /ID# 216566, Phoenix

85018-2111

HonorHealth /ID# 216642, Phoenix

85258-4582

Movement Disorders Center of Arizona /ID# 216503, Scottsdale

93710-5473

Neuro Pain Medical Center /ID# 216551, Fresno

91105-3149

SC3 Research Group - Pasadena /ID# 216821, Pasadena

80301-1880

Alpine Clinical Research Center /ID# 216637, Boulder

80210-7009

Denver Neurological Research, LLC /ID# 216784, Denver

80113-2736

Rocky Mountain Movement Disorders Center /ID# 216737, Englewood

32608-3928

Fixel Institute for Neurological Diseases /ID# 216514, Gainesville

33176-2148

Visionary Investigators Network - Miami /ID# 216679, Miami

33407-3209

Premiere Research Institute - Palm Beach /ID# 217207, West Palm Beach

02135-2907

St Elizabeth's Medical Center - Brighton /ID# 216716, Brighton

63005-1205

Clinical Research Professionals - Chesterfield /ID# 216669, Chesterfield

08648-2300

Global Neurosciences Institute /ID# 217875, Lawrenceville

14642-0001

University of Rochester /ID# 218737, Rochester

43210-1229

Ohio State University - Wexner Medical Center /ID# 216900, Columbus

43054-8167

The Orthopedic Foundation /ID# 217157, New Albany

74136-6378

The Movement Disorder Clinic of Oklahoma /ID# 216860, Tulsa

97232-2003

Legacy Research Institute /ID# 216558, Portland

19104-5502

University of Pennsylvania /ID# 216560, Philadelphia

29935-2029

Coastal Neurology /ID# 217190, Port Royal

37067-5914

KCA Neurology - Franklin /ID# 217419, Franklin

37232-0011

Vanderbilt University Medical Center /ID# 216675, Nashville

75231-4316

Kerwin Research Center /ID# 216587, Dallas

75243-1188

Neurology Consultants of Dallas - LBJ Fwy /ID# 216564, Dallas

78628-4126

Texas Movement Disorder Specialists /ID# 216523, Georgetown

23502-3932

Meridian Clinical Research /ID# 216731, Norfolk

23229-4913

Neurological Associates - Forest Ave /ID# 216636, Richmond

98122-5788

Swedish Neuroscience /ID# 216526, Seattle

99202-1342

Inland Northwest Research /ID# 221036, Spokane

53226-3522

Medical College of Wisconsin /ID# 216498, Milwaukee

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AbbVie

INDUSTRY