COVID-19: Human Epidemiology and Response to SARS-CoV-2

CompletedOBSERVATIONAL
Enrollment

5,599

Participants

Timeline

Start Date

May 1, 2020

Primary Completion Date

March 29, 2021

Study Completion Date

March 29, 2021

Conditions
Coronavirus Disease 2019 (COVID-19)SARS-CoV-2
Interventions
PROCEDURE

Collection of Biological Samples

Biological samples will be collected throughout the study at regular intervals (every 2 weeks) in addition to when illness event(s) occur. All biological samples (e.g. nasal swabs, peripheral blood, stool) will be collected by the caregiver at home using materials provided to the family. At the end of study, additional samples (e.g. nasal secretion and/or saliva samples) may be collected by the family or study staff at a site visit, if feasible.

PROCEDURE

Symptom and Exposure Surveys

Symptom and exposure surveys (questionnaires) will be completed throughout the study at regular intervals (every 2 weeks) in addition to when illness event(s) occur. The primary household contact/caregiver will be the designee for ensuring timely questionnaires completion and submission for all household study participants.

Trial Locations (20)

10032

Columbia University Medical Center: Inner City Asthma Consortium (ICAC) Site, New York

20010

Children's National Medical Center: Inner City Asthma Consortium (ICAC) Site, Washington D.C.

37232

Vanderbilt University Medical Center: Infant Susceptibility to Pulmonary Infections and Asthma Following RSV Exposure Study (INSPIRE) Site, Nashville

45229

Cincinnati Children's Hospital Medical Center: Greater Cincinnati Pediatric Clinic Repository (GCPCR) and Mechanisms of Progression of Atopic Dermatitis to Asthma in Children (MPAACH) Site, Cincinnati

Cincinnati Children's Hospital Medical Center: Inner City Asthma Consortium (ICAC) Site, Cincinnati

Cincinnati Children's Hospital Medical Center: Outcome Measures in Eosinophilic Gastrointestinal Disorders Across the Ages (OMEGA) Site, Cincinnati

Cincinnati Children's Hospital Medical Center:Cincinnati Childhood Allergy & Air Pollution Study (CCAAPS) Site, Cincinnati

48202

Henry Ford Health System: Childhood Allergy Study (CAS) Site, Detroit

Henry Ford Health System: Inner City Asthma Consortium (ICAC) Site, Detroit

Henry Ford Health System: Microbes, Asthma, Allergy and Pets (MAAP) and Wayne County Health, Environment, Allergy, and Asthma Longitudinal Study (WHEALS) Site, Detroit

53792

University of Wisconsin Hospital and Clinics: Childhood Origins of Asthma (COAST) Site, Madison

University of Wisconsin Hospital and Clinics: Wisconsin Infant Study Cohort (WISC) Site, Madison

60611

Ann & Robert H. Lurie Children's Hospital of Chicago: Food Allergy Outcomes Related to White and African American Racial Differences (FORWARD) and Improving Technology-Assisted Recording of Asthma Control in Children (iTRACC) Site, Chicago

63110

St. Louis Children's Hospital: Inner City Asthma Consortium (ICAC) Site, St Louis

75390

University of Texas Southwestern Medical Center: Inner City Asthma Consortium (ICAC) Site, Dallas

80045

Children's Hospital Colorado: Inner City Asthma Consortium (ICAC) Site, Aurora

Children's Hospital Colorado: Outcome Measures in Eosinophilic Gastrointestinal Disorders Across the Ages (OMEGA) Site, Aurora

02114

Massachusetts General Hospital:Childhood Microbiome (CHIME) and Wheezing Index (WIND) Site, Boston

02115

Boston Children's Hospital: School Inner-City Asthma Study (SICAS-2), Environmental Assessment of Sleep in Youth (EASY), Severe Asthma Research Program (SARP) and Preventing Asthma in High Risk Kids (PARK) Site, Boston

02118

Boston Medical Center: Inner City Asthma Consortium (ICAC) Site, Boston

All Listed Sponsors
collaborator

Rho Federal Systems Division, Inc.

INDUSTRY

lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT04375761 - COVID-19: Human Epidemiology and Response to SARS-CoV-2 | Biotech Hunter | Biotech Hunter