Effects of Sulawesi Propolis Extract on Lesion Growth, Apoptotic and Inflammatory Activity of the Rat Endometriosis Tissue

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

November 1, 2019

Primary Completion Date

May 18, 2020

Study Completion Date

May 18, 2020

Conditions
Endometriosis; PeritoneumEndometriosis
Interventions
DRUG

Dienogest

1mg/kg BW/day based on the study by Katayama et al. A DNG in 0,5% carboxymethylcellulose suspension was given orally with metal sound daily 0,2-0,4 mL per day

DRUG

Propolis

The propolis contains 20 mg in each ml. So, each rat we given 0,2 ml for 50mg/kg propolis treatment and 0,4 ml for 100mg/kg propolis treatment

OTHER

placebo

we gave 0,2 ml to each rat everyday to negative control groups, and we gave no treatment to sham groups

Trial Locations (1)

Unknown

Animal Laboratory of Indonesia University, Jakarta

All Listed Sponsors
lead

Indonesia University

OTHER

NCT04374006 - Effects of Sulawesi Propolis Extract on Lesion Growth, Apoptotic and Inflammatory Activity of the Rat Endometriosis Tissue | Biotech Hunter | Biotech Hunter