2,076
Participants
Start Date
March 24, 2021
Primary Completion Date
December 31, 2028
Study Completion Date
December 31, 2028
Motor Tests
To assess motor function annually
Cognitive Tests
To assess cognitive function annually
Unenhanced-MRI of the brain
The UE-MRI of the brain will be performed at baseline and at the year 5 visit in order to exclude presence of a significant MRI abnormality
Gadolinium Measurements
Blood samples and spontaneous urine specimens will be collected through the course of the study to measure Gd concentration
Gadoxetate disodium
Administered as defined by the treating physician as part of routine clinical practice
Gadobenate dimeglumine
Administered as defined by the treating physician as part of routine clinical practice
Gadodiamide
Administered as defined by the treating physician as part of routine clinical practice
Gadoterate meglumine
Administered as defined by the treating physician as part of routine clinical practice
Gadobutrol
Administered as defined by the treating physician as part of routine clinical practice
Gadoteridol
Administered as defined by the treating physician as part of routine clinical practice
RECRUITING
Seoul National University Bundang Hospital, Seongnam-si
RECRUITING
Penn State Hershey Medical Center, Hershey
RECRUITING
Albert Einstein Healthcare Network, Philadelphia
RECRUITING
Hallym University Chuncheon Sacred Heart Hospital, Chuncheon
RECRUITING
UNC School of Medicine, Chapel Hill
RECRUITING
Azienda Ospedaliera Universitaria di Trieste, Trieste
RECRUITING
Inje University Busan Paik Hospital, Busan
RECRUITING
Pusan National University Hospital, Busan
RECRUITING
A.O.U. Senese Policlinico Santa Maria alle Scotte, Siena
RECRUITING
University of Wisconsin, Madison
RECRUITING
University of Chicago Medical Center, Chicago
RECRUITING
Chosun University Hospital, Gwangju
RECRUITING
Chonnam National University Hospital, Gwangju
RECRUITING
Methodist Medical Center of Illinois, Peoria
WITHDRAWN
Department of Radiology, St Louis
RECRUITING
CHU Strasbourg - Hôpital Hautepierre, Strasbourg
ACTIVE_NOT_RECRUITING
Universitaetsklinikum Tuebingen, Tübingen
WITHDRAWN
Groupe Hospitalier Pitie-Salpetriere, Paris
RECRUITING
UT Southwestern Medical Center, Dallas
NOT_YET_RECRUITING
MD Anderson Cancer Center, Houston
RECRUITING
Scottsdale Medical Imaging, LLC, Scottsdale
SUSPENDED
"FSBI National medical scientific center of psychiatry and neurology n.a. V.M. Bekhterev Adolescent", Saint Petersburg
SUSPENDED
FSBI North-West Federal Medical Research Center n.a. V.A. Almazov of MoH RF, Saint Petersburg
SUSPENDED
LLC Medical Center Mart, Saint Petersburg
SUSPENDED
"RSBIH Smolensk Regional Clinical Hospital", Smolensk
SUSPENDED
SBIH Republican Clinical Oncological Dispensary of the MoH of Republic Bashkortostan, Ufa
SUSPENDED
"Federal State Budgetary Scientific Institution Tomsk National Research Medical Centre of the Russia", Tomsk
SUSPENDED
"BHI of Omsk region Clinical Oncology Dispensary", Omsk
WITHDRAWN
Yale University School of Medicine, New Haven
RECRUITING
Massachussets General Hospital, Boston
RECRUITING
Boston University Medical Center, Boston
RECRUITING
Beth Israel Deaconess Medical Center, Boston
RECRUITING
ActivMed Practices & Research, Inc., Methuen
RECRUITING
University of Massachusetts Memorial Medical Center, Worcester
TERMINATED
Hospital Santa Marta, Taguatinga
RECRUITING
Liga Norte-Rio-Grandense Contra o Câncer, Natal
RECRUITING
Instituto Mederi de Pesquisa e Saude, Passo Fundo
RECRUITING
Hospital Moinhos de Vento, Porto Alegre
RECRUITING
Instituto Baía Sul de Ensino e Pesquisa (IEP), Florianópolis
RECRUITING
CEMEC - Oncológica, São Bernardo do Campo
RECRUITING
Fundação Faculdade Regional de Medicina de São José do Rio Preto, São José do Rio Preto
RECRUITING
CPCLIN - Centro de Pesquisas Clínicas Ltda., São Paulo
RECRUITING
Albert Einstein Sociedade Beneficente Israelita Brasileira, São Paulo
WITHDRAWN
CEMEC - Oncológica, São Bernardo do Campo
WITHDRAWN
G. Kenneth Jansz Medical Professional Corporation, Burlington
RECRUITING
Gangnam Severance Hospital, Yonsei University Health System, Seoul
RECRUITING
Chung-Ang University Hospital, Seoul
Lead Sponsor
Bayer AG (Sponsor)
UNKNOWN
Bracco (Sponsor)
UNKNOWN
GEHC (Sponsor)
UNKNOWN
Guerbet
INDUSTRY