1,210
Participants
Start Date
January 31, 2014
Primary Completion Date
July 31, 2017
Study Completion Date
February 28, 2019
Hydrochlorothiazide, Captopril, Nitrendipine, Aspirin
The participants were grouped into a control group and a TDP group. Hypertension of patients in the control group was managed with the original protocol by doctors in village clinics. Patients in the TDP group were supplied with the TDP treatment, for whom different levels of oral administration plans to patients without drugs treatment in original protocol were: G 0 and G I, nifedipine (20mg, bid) or captopril (25mg, tid), hydrochlorothiazide (12.5mg, bid) for patients who couldn't tolerate previous drugs; G II, nifedipine (20mg, bid) plus hydrochlorothiazide (12.5mg, bid), or captopril (25mg, tid) plus hydrochlorothiazide (12.5mg, bid ), triple therapy for patients whose blood pressure did not reach target BP; G III, three drugs combination. Patients with drugs treatments in the original protocol were changed to be treated with the above antihypertension medications which were uniformly supplied by the government.
the first affiliated hospital of Xi'an Jiaotong university, Xi'an
First Affiliated Hospital Xi'an Jiaotong University
OTHER