688
Participants
Start Date
June 4, 2020
Primary Completion Date
April 30, 2024
Study Completion Date
April 30, 2026
Radical colectomy
Patients undergo radical resection of the primary colorectal cancer(open or laparoscopic/robotic)
HIPEC
HIPEC(simultaneously or within 2days after resection) with mitomycin c (30 mg/m2) at 43°C for 90 minutes.
Systemic chemotherapy
"Systemic chemotherapy regimens: CapeOx and mFOLFOX6 are preferred for stage Ⅲ patients.~CapeOx:oxaliplatin 130 mg/m2 IV d1 + capecitabine 1000mg/m2 po bid d1-14. Repeat every three weeks for eight cycles.~mFOLFOX6:oxaliplatin 85 mg/m2 IV d1 + leucovorin calcium 400 mg/m2 IV d1 + 5-FU 400 mg/m2 IV bolus d1 + 5-FU 2400 mg/m2 continuous IV over 46-48 hours d1-2. Repeat every two weeks for twelve cycles.~For stageⅡpatiens, regimens recommend by NCCN guide line(2019 v1) are acceptable."
NOT_YET_RECRUITING
Peking University People's Hospital, Beijing
RECRUITING
Union Hospital,Tongji Medical College, Huazhong Uninersity of Science and Technolgy, Wuhan
NOT_YET_RECRUITING
Sun Yat-sen University Cancer Center, Guangzhou
NOT_YET_RECRUITING
Guangdong Provincal people's Hospital, Guangzhou
RECRUITING
Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou
NOT_YET_RECRUITING
Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou
NOT_YET_RECRUITING
Nanfang Hospital of Southern Medical University, Guangzhou
RECRUITING
Sichuan Provincial People's Hospital, Chengdu
NOT_YET_RECRUITING
Beijing Hospital, Beijing
NOT_YET_RECRUITING
Cancer Hospital Chinese Academy of Medical Sciences, Beijing
NOT_YET_RECRUITING
Peking University Cancer Hospital & Institute, Beijing
NOT_YET_RECRUITING
Chongqing Cancer Hospital, Chongqing
NOT_YET_RECRUITING
First Affiliated Hospital of Chongqing Medical University, Chongqing
NOT_YET_RECRUITING
Second Affiliated Hospital of Chongqing Medical University, Chongqing
NOT_YET_RECRUITING
The First People's Hospital of FoShan (Affiliated FoShan Hospital of Sun Yat-sen University), Foshan
NOT_YET_RECRUITING
The First Affiliated Hospital, Sun Yat-sen University, Guangzhou
NOT_YET_RECRUITING
The Six Affiliated Hospital,Sun Yat-sen University, Guangzhou
NOT_YET_RECRUITING
JiangMen Central Hospital Affiliated JiangMen Hospital Of SUN YAT-SEN University, Jiangmen
RECRUITING
MeiZhou People's Hospital, Meizhou
NOT_YET_RECRUITING
Affiliated Shantou Hospital of Sun Yat-sen University, Shantou
NOT_YET_RECRUITING
Shenzhen Second People's Hospital, Shenzhen
NOT_YET_RECRUITING
Zhongshan City People's Hospital, Zhongshan
NOT_YET_RECRUITING
Zhuhai People's Hospital, Zhuhai hospital affiliated with Jinan University, Zhuhai
NOT_YET_RECRUITING
People's hospital of guangxi zhuang autonomous region, Nanning
NOT_YET_RECRUITING
The Affiliated Tumor Hospital of Guangxi Medical University, Nanning
NOT_YET_RECRUITING
Hebei Medical University Fourth Hospital, Shijiazhuang
NOT_YET_RECRUITING
Wuhan University Renmin Hospital, Wuhan
NOT_YET_RECRUITING
Zhongnan Hospital of Wuhan University, Wuhan
NOT_YET_RECRUITING
The Affiliated Hospital of Xuzhou Medical University, Xuzhou
NOT_YET_RECRUITING
the First Affiliated Hospital of Nanchang University, Nanchang
NOT_YET_RECRUITING
Fudan University Shanghai Cancer Center, Shanghai
NOT_YET_RECRUITING
The Third Peoples' Hospital of Chengdu, Chengdu
NOT_YET_RECRUITING
West China Hospital，Sichuan University, Chengdu
NOT_YET_RECRUITING
People'S Hospital of Deyang City, Deyang
NOT_YET_RECRUITING
Leshan people's Hospital, Leshan
NOT_YET_RECRUITING
The Affiliated hospital of southwest medical university, Luzhou
NOT_YET_RECRUITING
The Second Affiliated Hospital，Zhejiang University School of Medicine, Hangzhou
Nanfang Hospital, Southern Medical University
OTHER
Sun Yat-sen University
OTHER
Sixth Affiliated Hospital, Sun Yat-sen University
OTHER
First Affiliated Hospital, Sun Yat-Sen University
OTHER
Guangdong Provincial Hospital of Traditional Chinese Medicine
OTHER
Guangdong Provincial People's Hospital
OTHER
Meizhou People's Hospital
OTHER
First People's Hospital of Foshan
OTHER
Shantou Central Hospital
OTHER
Jiangmen Central Hospital
OTHER
Shenzhen Second People's Hospital
OTHER
Zhongshan People's Hospital, Guangdong, China
OTHER
ZhuHai Hospital
OTHER
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
OTHER
Beijing Hospital
OTHER_GOV
Peking University Cancer Hospital & Institute
OTHER
Peking University People's Hospital
OTHER
Fudan University
OTHER
The Second Affiliated Hospital of Chongqing Medical University
OTHER
Chongqing University Cancer Hospital
OTHER
First Affiliated Hospital of Chongqing Medical University
OTHER
Second Affiliated Hospital, School of Medicine, Zhejiang University
OTHER
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
OTHER
Renmin Hospital of Wuhan University
OTHER
Wuhan University
OTHER
Sichuan Provincial People's Hospital
OTHER
West China Hospital
OTHER
The People's Hospital of Leshan
OTHER
People's Hospital of Deyang City
UNKNOWN
Hebei Medical University Fourth Hospital
OTHER
The First Affiliated Hospital of Nanchang University
OTHER
The Affiliated Hospital Of Southwest Medical University
OTHER
The Affiliated Hospital of Xuzhou Medical University
OTHER
People's Hospital of Guangxi Zhuang Autonomous Region
OTHER
The Third People's Hospital of Chengdu
OTHER
The Affiliated Tumor Hospital of Guangxi Medical University
UNKNOWN
Affiliated Cancer Hospital & Institute of Guangzhou Medical University
OTHER