Antibacterial Effect and Clinical Performance of Chitosan Modified Glass Ionomer

PHASE3CompletedINTERVENTIONAL
Enrollment

65

Participants

Timeline

Start Date

January 15, 2019

Primary Completion Date

January 5, 2021

Study Completion Date

January 5, 2021

Conditions
Reversible PulpitisPulpitisCaries,DentalCaries Class ICaries; DentinCaries
Interventions
DRUG

Glass Ionomer

Glass ionomer filling material would be modified accordingly or used as is

DRUG

Chitosan Low Molecular Weight (20-200 Mpa.S)

deacetylated chitin, poly(D-glucosamine) purified by dissolving in 0.1 mol/L acetic acid, then precipitated in 0.1 mol/L sodium hydroxide and the precipitate will be washed with ethanol/water (70/30 v/v) mixture followed by freeze drying

DRUG

Chlorhexidine Diacetate

Chlorhexidine antibacterial effect to be compared by Sigma-aldrich PHR 1222 , lot#LRAB3716

DRUG

Titanium Dioxide

Titanium(IV) oxide,nanopowder, 21 nm primary particle size (TEM), \>99.5% trace metals basis cat#718467 Lot#MKCB6332 Lot #MKCB6332

Trial Locations (1)

1156

Faculty of Dentistry, Ain Shams University, Cairo

All Listed Sponsors
lead

Ain Shams University

OTHER

NCT04365270 - Antibacterial Effect and Clinical Performance of Chitosan Modified Glass Ionomer | Biotech Hunter | Biotech Hunter