NGS Diagnostic in COVID-19 Hosts - Genetic Cause Relating to the Course of Disease Progression

NACompletedINTERVENTIONAL
Enrollment

1,000

Participants

Timeline

Start Date

October 21, 2020

Primary Completion Date

April 30, 2023

Study Completion Date

August 31, 2023

Conditions
COVID-19
Interventions
GENETIC

Whole Genome Analysis

Whole Genome Analysis with whole transcriptome analysis and deoxyribonucleic acid (DNA) methylation analysis using Methylation beadchip (EPIC) arrays

GENETIC

T-cell receptor (TCR) repertoire

Longitudinal analysis of TCR repertoire of Cluster of Differentiation 4+ (CD4+) and CD8+ T cells from blood samples (Peripheral Blood Mononuclear Cells, PBMCs) from clinically characterized patients

GENETIC

SARS-CoV-2 viral composition

Determined by Next Generation sequencing

Trial Locations (1)

72076

University Hospital Tübingen, Tübingen

All Listed Sponsors
lead

University Hospital Tuebingen

OTHER

NCT04364828 - NGS Diagnostic in COVID-19 Hosts - Genetic Cause Relating to the Course of Disease Progression | Biotech Hunter | Biotech Hunter