CONTAIN COVID-19: Convalescent Plasma to Limit COVID-19 Complications in Hospitalized Patients

PHASE2CompletedINTERVENTIONAL
Enrollment

941

Participants

Timeline

Start Date

April 17, 2020

Primary Completion Date

March 29, 2021

Study Completion Date

December 12, 2022

Conditions
COVID-19CoronavirusCoronavirus Infection
Interventions
BIOLOGICAL

Convalescent Plasma

SARS-CoV-2 convalescent plasma (1-2 units; \~250-500 mL) with antibodies to SARS-CoV-21 per April 13, 2020 directive by the FDA, obtained from New York Blood Center will be administered to eligible candidate

OTHER

Saline solution

Equivalent volume of saline solution (defined as half-,quarter-, or normal saline) will be administered to eligible candidate as a placebo control group.

Trial Locations (9)

10003

NYU Langone Health, New York

10467

Montefiore Medical Center, The Bronx

33136

University of Miami Hospital and Clinics, Miami

53215

Aurora St. Luke's Medical Center, Milwaukee

53226

Medical College of Wisconsin / Froedtert Memorial Lutheran Hospital, Milwaukee

75701

The University of Texas Health Science Center, Tyler

77030

The University of Texas Health Science Center, Houston

78539

University of Texas Rio Grande Valley, Edinburg

06520

Yale University School of Medicine, New Haven

All Listed Sponsors
collaborator

National Center for Advancing Translational Sciences (NCATS)

NIH

collaborator

Albert Einstein College of Medicine

OTHER

collaborator

Yale University

OTHER

collaborator

The University of Texas Health Science Center, Houston

OTHER

collaborator

The University of Texas Health Science Center at Tyler

OTHER

collaborator

University of Miami

OTHER

lead

NYU Langone Health

OTHER

NCT04364737 - CONTAIN COVID-19: Convalescent Plasma to Limit COVID-19 Complications in Hospitalized Patients | Biotech Hunter | Biotech Hunter