D2 vs D3 Lymph Node Dissection for Left Colon Cancer

NARecruitingINTERVENTIONAL
Enrollment

1,381

Participants

Timeline

Start Date

March 31, 2020

Primary Completion Date

December 31, 2028

Study Completion Date

December 31, 2033

Conditions
Colon Cancer
Interventions
PROCEDURE

Left colon resection

"This procedure is performed for tumours in splenic flexure and proximal and descending colon.~Left colic artery is divided at its origin. Sigmoid arteries and superior rectal arteries are preserved. Inferior mesenteric vein is divided at the lower border of the pancreas. The colon is divided about 10 cm proximal and distal to the tumour. Mesocolic fascia is preserved and the length of the vessel trunk of the mesocolon corresponds to the level of lymph node dissection. After removal of the resected colonic segment a handsewn or stapler end-to-end or side-to-side colonic anastomosis is performed."

PROCEDURE

Sigmoid colon resection

"This procedure is performed for tumours in sigmoid colon. Corresponding sigmoid arteries are divided at their origin. Left colic artery and superior rectal artery are preserved. Inferior mesenteric vein is divide close to the left colic artery. Proximal and distal margin compose 10 cm from the tumour. Mesocolic fascia is preserved and the length of the vessel trunk of the mesocolon corresponds to the level of lymph nodes dissection. After removal of the resected colonic segment a handsewn end-to-end or side-to-side or stapler colonic anastomosis is performed."

PROCEDURE

Distal sigmoid colon resection or anterior resection

"This procedure is performed for tumours in distal sigmoid colon or rectosigmoid junction. Superior rectal artery is divided below the origin of left colic artery. Left colic artery is preserved. Inferior mesenteric vein is divide close to the left colic artery. The colon is divided about 10 cm proximal and 5 cm distal to the tumour. Mesocolic fascia is preserved and the length of the vessel trunk of the mesocolon corresponds to the level of lymph node dissection. After removal of the resected colonic segment handsewn or stapler colo-rectal anastomosis is performed."

Trial Locations (1)

119435

RECRUITING

Clinic of coloproctology and minimally invasive surgery, Moscow

All Listed Sponsors
collaborator

I.M. Sechenov First Moscow State Medical University

OTHER

collaborator

G.V. Bondar Republican Cancer Center

OTHER

lead

Russian Society of Colorectal Surgeons

OTHER