50
Participants
Start Date
April 27, 2020
Primary Completion Date
January 11, 2021
Study Completion Date
January 11, 2021
hypoxia : 14.3 and 12.7% FIO2, hypercapnia 7% CO2, inspiratory mechanical constraint
the fraction of inspired oxygen is reduced from \~21% (room air) to 14.3 and 12.7% allowing the SpO2 to decrease to \~75%, rebreathing test allowing the PCO2 to rise to 65 mmHg, inspiratory mechanical constraint with 50 to 75% of maximum inspiratory pressure
Département R3S, hôpital de la pitié-salpêtrière, Paris
Assistance Publique - Hôpitaux de Paris
OTHER