Lipid Peroxidation and Options Antioxidant Therapy for Secondary Lymphedema of the Lower Extremities

PHASE4CompletedINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

September 1, 2019

Primary Completion Date

August 3, 2022

Study Completion Date

August 3, 2022

Conditions
Lower Extremity Lymphedema
Interventions
DRUG

Micronised purified flavonoid fraction (diosmin+flavonoids expressed as hesperidin)

Micronised purified flavonoid fraction (diosmin+flavonoids expressed as hesperidin) is prescribed at a dose of 1000 mg / day Tocopherol is prescribed at a dose of 400 ME/ day

DRUG

Tocopherol

patients with lower limb lymphedema receiving conservative therapy (elastic compression, to which are added preparations with antioxidant endotheliotropic activity (Tocopherol-400 IU/day)

OTHER

Elastic compression

patients with lower limb lymphedema receiving conservative therapy that includes only the use of elastic compression

Trial Locations (1)

390026

Ryazan State Medical University, Ryazan

All Listed Sponsors
lead

Ryazan State Medical University

OTHER

NCT04360889 - Lipid Peroxidation and Options Antioxidant Therapy for Secondary Lymphedema of the Lower Extremities | Biotech Hunter | Biotech Hunter