Ketamine Versus Magnesium Sulfate in the Time and Awakening Quality of General Anesthesia.

NARecruitingINTERVENTIONAL
Enrollment

140

Participants

Timeline

Start Date

March 14, 2022

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Awakening, Post-Anesthesia Delayed
Interventions
OTHER

General anesthesia

Balanced general anesthesia. Induction with lidocaine, fentanyl, propofol and cisatracurium. Maintenance with sevoflurane.

DRUG

Ketamine plus general anesthesia

ketamine 0.3 mg / kg 15 minutes before balanced general anesthesia. Induction with lidocaine, fentanyl, propofol and cisatracurium. Maintenance with sevoflurane.

DRUG

Magnesium sulfate plus general anesthesia

Magnesium sulfate 40 mg / kg 15 minutes before balanced general anesthesia. Induction with lidocaine, fentanyl, propofol and cisatracurium. Maintenance with sevoflurane.

DRUG

ketamine plus magnesium sulfate plus general anesthesia

Ketamine 0.15 mg/kg plus magnesium sulfate 20 mg/kg 15 minutes before balanced general anesthesia. Induction with lidocaine, fentanyl, propofol and cisatracurium. Maintenance with sevoflurane

Trial Locations (1)

11065910

RECRUITING

Hospital da Beneficência Portuguesa de Santos, Santos

All Listed Sponsors
lead

University of Sao Paulo General Hospital

OTHER