Ruxolitinib for Treatment of Covid-19 Induced Lung Injury ARDS

PHASE2CompletedINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

July 1, 2020

Primary Completion Date

December 31, 2020

Study Completion Date

July 30, 2021

Conditions
ARDS, HumanCOVID
Interventions
DRUG

Ruxolitinib administration

Ruxolitinib will be administered p.o. or by gavage feeding starting with 2 x 10mg or 2 x 15mg bid dose at day 1 according to the investigator's decision and can be increased up to 2 x 15mg bid from day 2 to day 28 (max) (depending on platelet counts and renal function). Ruxolitinib will be administered in the morning and evening. Dosing will be adjusted according to toxicity and kidney function.If the patient is discharged before day 28, the therapy will be discontinued for discharge.

Trial Locations (1)

D-35043

Andreas Neubauer, Marburg

All Listed Sponsors
lead

Philipps University Marburg

OTHER

NCT04359290 - Ruxolitinib for Treatment of Covid-19 Induced Lung Injury ARDS | Biotech Hunter | Biotech Hunter