15
Participants
Start Date
July 1, 2020
Primary Completion Date
December 31, 2020
Study Completion Date
July 30, 2021
Ruxolitinib administration
Ruxolitinib will be administered p.o. or by gavage feeding starting with 2 x 10mg or 2 x 15mg bid dose at day 1 according to the investigator's decision and can be increased up to 2 x 15mg bid from day 2 to day 28 (max) (depending on platelet counts and renal function). Ruxolitinib will be administered in the morning and evening. Dosing will be adjusted according to toxicity and kidney function.If the patient is discharged before day 28, the therapy will be discontinued for discharge.
Andreas Neubauer, Marburg
Philipps University Marburg
OTHER