A Study to Evaluate the Effect of Vagus Nerve Stimulation in Patients Undergoing VT Ablation

NACompletedINTERVENTIONAL
Enrollment

5

Participants

Timeline

Start Date

December 8, 2020

Primary Completion Date

June 30, 2023

Study Completion Date

October 30, 2023

Conditions
ArrhythmiaVentricular Tachycardia (VT)
Interventions
OTHER

Vagus Nerve Stimulation (VNS)

Vagus Nerve Stimulation (VNS) will be performed percutaneously through the internal jugular vein during the patient's routine VT ablation procedure. The nerve will be stimulated using standard pacing systems used for clinical purposes. A series of stimulation frequencies and pulse widths will be used to define optimal effects and 'dosing'. Activation recovery interval (ARI) will be measured from the unipolar electrograms. In addition, heart rate and blood pressure responses will be continuously recorded.

Trial Locations (1)

90095

UCLA Health, Los Angeles

All Listed Sponsors
collaborator

National Institutes of Health (NIH)

NIH

lead

University of California, Los Angeles

OTHER

NCT04359004 - A Study to Evaluate the Effect of Vagus Nerve Stimulation in Patients Undergoing VT Ablation | Biotech Hunter | Biotech Hunter