Non-invasive Diagnosis of Invasive Pulmonary Aspergillosis by Use of Biomarkers in Exhaled Breath Condensate

CompletedOBSERVATIONAL
Enrollment

101

Participants

Timeline

Start Date

April 17, 2020

Primary Completion Date

December 31, 2023

Study Completion Date

December 31, 2023

Conditions
Aspergillosis PneumoniaPneumocystis Pneumonia
Interventions
DIAGNOSTIC_TEST

Aspergillus specific proteins in exhaled breath condensate (EBC)

The EBC will be collected by use of the RTube(R) system which is commercially available for the purpose of collection of EBC. As the patient breathes through a mouth piece, the exhaled breath is lead through a cooling chamber where the vaporous part of the exhaled breath condenses. The investigators aim at collecting a total minimum of 3.0 mL EBC per study participant in order to have sufficient amount of protein for the subsequent analysis.

DIAGNOSTIC_TEST

Pneumocystis jirovecii DNA in exhaled breath condensate (EBC)

The EBC will be collected by use of the RTube(R) system which is commercially available for the purpose of collection of EBC. As the patient breathes through a mouth piece, the exhaled breath is lead through a cooling chamber where the vaporous part of the exhaled breath condenses. The investigators aim at collecting a total minimum of 3.0 mL EBC per study participant in order to have sufficient amount of protein for the subsequent analysis.

Trial Locations (1)

9000

Aalborg Hospital, Aalborg

All Listed Sponsors
collaborator

Aarhus University Hospital

OTHER

lead

Inger Lise Gade

OTHER

NCT04358419 - Non-invasive Diagnosis of Invasive Pulmonary Aspergillosis by Use of Biomarkers in Exhaled Breath Condensate | Biotech Hunter | Biotech Hunter