175
Participants
Start Date
April 28, 2020
Primary Completion Date
February 14, 2022
Study Completion Date
June 2, 2022
Thrombin generation test assay
lag time, initial velocity, time-to-peak, thrombin peak, total thrombin generation time, extrinsic thrombin potential (ETP). Crude quantitative values and relative values (%, by reference to the one obtained with an invariant reference plasma). Both without the addition of purified thrombomodulin (TM-) and with the addition of purified thrombomodulin (TM+). The ability of TM to inhibit thrombin generation will be calculated as follows: \[ETP (%)(TM+) / ETP (%)(TM-)\].
Fibrin generation markers assays
D-dimers (coagulation plus fibrinolysis), soluble fibrin monomers (coagulation only)
CHU de Bordeaux, Bordeaux
CHU de Limoges, Limoges
CHU de Montpellier, Montpellier
CHU de Nimes, Nîmes
Centre Hospitalier Universitaire de Nīmes
OTHER