22
Participants
Start Date
November 11, 2014
Primary Completion Date
February 18, 2020
Study Completion Date
February 18, 2020
Sildenafil
Initial Sildenafil dosage will be weight dependent. Participants will start at 40 mg daily (20mg in the morning, 20 mg in the evening) or 60 mg daily (40mg in the morning and 20 mg in the evening). Sildenafil dosage may be increased to up to 80mg daily (20-40mg in the morning and 20-40mg in the evening) based on the response to lower doses. If the participant has not had improvement after initial treatment, the dose may be increased, at the discretion of the study physician.
Standard of Care Sildenafil
Medical record review of participants that receive Sildenafil as part of standard of care.
Ocular Coherence Tomography-Angiography (OCT-A)
Retinal photographs will be taken at each study visit.
Visual Acuity (VA)
Visual acuity will be measured with Snellen Eye Chart at each study visit.
Columbia University Medical Center, Edward Harkness Eye Institute, New York
Columbia University
OTHER