NCT04353778View on ClinicalTrials.gov

Effects of Vagal Dysfunction on Gastrointestinal and Inflammatory Pathways in HIV

PHASE1/PHASE2Enrolling by invitationINTERVENTIONAL
Enrollment

55

Participants

Timeline

Start Date

August 3, 2020

Primary Completion Date

January 31, 2026

Study Completion Date

January 31, 2026

Conditions
HIVNon-HIVVagus Nerve Dysfunction
Interventions
DRUG

Pyridostigmine

Eight weeks of low-dose pyridostigmine

DRUG

Placebos

matching placebo x 8 weeks

PROCEDURE

non-invasive vagal nerve stimulation

stimulation of the vagus nerve

Trial Locations (1)

10029

Icahn School of Medicine at Mount Sinai, New York

All Listed Sponsors
collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

lead

Icahn School of Medicine at Mount Sinai

OTHER