Transmuscular Quadratus Lumborum Block Plus Pericapsular Injection vs Pericapsular Injection

PHASE4CompletedINTERVENTIONAL
Enrollment

104

Participants

Timeline

Start Date

August 1, 2020

Primary Completion Date

February 17, 2022

Study Completion Date

February 23, 2022

Conditions
Hip Pain Chronic
Interventions
PROCEDURE

Transmuscular Quadratus Lumborum Block

Transmuscular Quadratus Lumborum Block (TQLB) is a relatively new block that targets thoracic and lumbar nerves. The decrease in sensation means a decrease in pain. The TQL block will be preformed in addition to an incision-site injection (on hip), called pericapsular injection. The potential risks associated with the Transmuscular Quadratus Lumborum Block (TQLB) include nerve damage and infection at injection site. In addition, there can be temporary sensory and motor loss, depending on the dosage, site of injection and duration of the nerve block. However, the amount (30mL) used in this study meets FDA dosage-regulations for this medication.

PROCEDURE

Pericapsular injection

Pericapsular injection (PCI) of 20 mL of 0.25% Bupivacaine HCL (numbing medication) into the incision-site (hip portal sites) to decrease sensation. The potential risks associated with the pericapsular injection include bleeding, infection at injection site and local anesthetic toxicity however, the likelihood is low due to the expertise of the surgeon preforming the injection and the sterile environment and good clinical practice from clinicians, which reduces the likelihood of infection.

DRUG

Bupivacaine Hydrochloride

Bupivacaine used for this study is the standard of care for both TQLB and PCI. Pericapsular injection (PCI) contains 10 mL of 0.25% Bupivacaine HCL which will be injected through the anterolateral portal while the additional 10 mL will be injected through the mid-anterior portal.

Trial Locations (1)

10016

NYU Langone Health, New York

All Listed Sponsors
lead

NYU Langone Health

OTHER

NCT04353414 - Transmuscular Quadratus Lumborum Block Plus Pericapsular Injection vs Pericapsular Injection | Biotech Hunter | Biotech Hunter