Effect of Individualized Versus Standard Bp Management During MT for Anterior Ischemic Stroke

NACompletedINTERVENTIONAL
Enrollment

433

Participants

Timeline

Start Date

March 8, 2021

Primary Completion Date

January 16, 2024

Study Completion Date

January 16, 2024

Conditions
Acute Cerebrovascular Accident
Interventions
PROCEDURE

Individualized blood pressure

Individualized blood pressure management during mechanical thrombectomy with the administration of diluted norepinephrine (5-10 µg/ml) or nicardipine (1 mg/ml) or urpidil (5 mg/ml) to maintain the MAP within 10% of the first MAP measured in the angiography suit

PROCEDURE

Standard blood pressure

Standard blood pressure management based on international guidelines: Treatment of hypotension defined by a systolic blood pressure \<140 mm Hg, and treatment of hypertension defined by a systolic blood pressure \> 180 mm Hg or diastolic blood pressure \>105 mm Hg) with usual treatments (norepinephrine, ephedrine or phenylephrine for hypotension; intravenous nicardipine or uradipil for hypertension).

Trial Locations (1)

Unknown

Hôpital Fondation Adolphe de Rothschild, Paris

All Listed Sponsors
collaborator

Ministry of Health, France

OTHER_GOV

lead

Fondation Ophtalmologique Adolphe de Rothschild

NETWORK

NCT04352296 - Effect of Individualized Versus Standard Bp Management During MT for Anterior Ischemic Stroke | Biotech Hunter | Biotech Hunter