Plinabulin vs. Pegfilgrastim in Patients With Solid Tumors Receiving Docetaxel Myelosuppressive Chemotherapy Phase 2

PHASE2CompletedINTERVENTIONAL
Enrollment

55

Participants

Timeline

Start Date

April 5, 2017

Primary Completion Date

March 20, 2018

Study Completion Date

April 20, 2018

Conditions
Chemotherapy-induced Neutropenia
Interventions
DRUG

Plinabulin

a synthetic, low molecular weight, new chemical entity that belongs to the diketopiperazine class of compounds. Plinabulin is intended for intravenous (IV) infusion and is diluted in D5W and administered for 30 minutes (± 5 minutes).

DRUG

Pegfilgrastim

PEGFILGRASTIM is a long-acting granulocyte colony-stimulating factor that stimulates the growth of neutrophils, to reduce the incidence of fever and infection in patients with certain types of cancer who are receiving chemotherapy that affects the bone marrow.

Trial Locations (19)

25011

Kirovograd Regional Oncological Center, Kropyvnytskyi

31021

Cancer Center of Middle Georgia, Dublin

32763

Mid Florida Hematology & Oncology Center, Orange City

40022

"Municipal Institution Sumy Regional Clinical Oncology Dispensary", Sumy

49102

Municipal Institution Dnipropetrovsk City Multi-functional Hospital, Dnipro

50048

"Regional Municipal Institution Kryvyy Rig Oncology Dispensary", Krivói Rog

60076

Hematology/Oncology of the North Shore, Skokie

73000

Kherson regional oncological dispensary Communal Institution of Kherson Regional council, Kherson

76000

Prykarpatian Clinical Oncological Center, Ivano-Frankivsk

79031

Lviv State Oncological Regional Treatment and Preventive Center, Lviv

88000

Zakarpattia Regional Clinical Oncology Center, Uzhhorod

92373

Emad Ibrahim, MD, Inc., Redlands

150000

Harbin Medical University Cancer Hospital, Harbin

210000

Jiangsu Cancer Hospital, Nanjing

354067

"SBI of Healthcare Oncology Dispensary #2 Ministry of Healthcare of Krasnodar Region", Sochi

400138

Volgograd Regional Clinical Oncology Dispensary, Volgograd

443001

Medical University 'REAVIZ', Samara

450008

Henan Cancer Hospital, Zhengzhou

03115

Kyiv City Clinical Oncology Center, Kyiv

All Listed Sponsors
lead

BeyondSpring Pharmaceuticals Inc.

INDUSTRY