NCT04341844View on ClinicalTrials.gov

Intraoperative Infusion of Methylene Blue for Prevention of Postoperative Delirium and Cognitive Dysfunction in Elderly Patients Undergoing Major Elective Noncardiac Surgery

NACompletedINTERVENTIONAL
Enrollment

248

Participants

Timeline

Start Date

January 14, 2019

Primary Completion Date

April 30, 2020

Study Completion Date

July 30, 2020

Conditions
Postoperative DeliriumPostoperative Cognitive Dysfunction
Interventions
DRUG

Methylene Blue

2mg/kg MB diluted with normal saline into total 50 ml volume intravenous administration after induction of anesthesia within one hour.

DRUG

Placebo

normal saline in total 50 ml volume intravenous administration after induction of anesthesia within one hour.

Trial Locations (1)

200040

Huashan Hospital, Shanghai

All Listed Sponsors
lead

Fudan University

OTHER

NCT04341844 - Intraoperative Infusion of Methylene Blue for Prevention of Postoperative Delirium and Cognitive Dysfunction in Elderly Patients Undergoing Major Elective Noncardiac Surgery | Biotech Hunter | Biotech Hunter