Open Radical Prostatectomy and Erector Spinae Plane Block

NACompletedINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

May 1, 2020

Primary Completion Date

January 11, 2021

Study Completion Date

January 11, 2021

Conditions
Prostate CancerAnesthesia, LocalPain, Postoperative
Interventions
PROCEDURE

Single-injection ultrasound-guided bilateral erector spinae plane (ESP) block-Sham

"With the patient in the sitting position, 20 ml normal saline will be administered between the T11 spinous process and the erector spinae muscles with the guidance of an ultrasound probe placed on a parasagittal plane.~Intraoperative analgesia: after anesthesia induction, paracetamol 1 gr intravenous (IV)+ tenoxicam 20 mg IV + morphine 0.05 mg/kg IV (max 4 mg).~Postoperative analgesia: IV morphine patient-controlled analgesia (PCA) of 0.5 mg/ml morphine (demand dose 1 mg; lockout interval 8 m; 6 mg/h limit)."

PROCEDURE

Single-injection ultrasound-guided bilateral erector spinae plane block-Lidocaine/Bupivacaine

"With the patient in the sitting position, 10 ml 1% lidocaine + 10 ml 0.5% bupivacaine will be administered between the T11 spinous process and the erector spinae muscles with the guidance of an ultrasound probe placed on a parasagittal plane.~Intraoperative analgesia: After anesthesia induction, paracetamol 1 gr IV + tenoxicam 20 mg IV + morphine 0.05 mg/kg IV (max 4 mg).~Postoperative analgesia: IV PCA of 0.5 mg/ml morphine (demand dose 1 mg; lockout interval 8 m; 6 mg/h limit)."

OTHER

Pain follow-up and monitorization

Numeric Rating Scale (NRS) pain score will be recorded from 15th minute in recovery room followed by 1.-3.-6.-12.-18.-24.hours with two different conditions which are at rest and while couching.If NRS score becomes ≥4 Dexketoprofen 50 mg will be administered (max 4 times).

Trial Locations (1)

55139

Ondokuz Mayis University, Samsun

All Listed Sponsors
collaborator

Ondokuz Mayıs University

OTHER

lead

BURHAN DOST

OTHER

NCT04337060 - Open Radical Prostatectomy and Erector Spinae Plane Block | Biotech Hunter | Biotech Hunter