Effect of Testosterone Treatment on Clitoral Arteries' Hemodynamic Parameters.

CompletedOBSERVATIONAL
Enrollment

81

Participants

Timeline

Start Date

March 20, 2019

Primary Completion Date

December 31, 2019

Study Completion Date

March 31, 2020

Conditions
Hypoactive Sexual Desire DisorderVulvovaginal DiseaseMenopause Related ConditionsDyspareunia (Female Excluding Psychogenic)HypoestrogenismArousal Disorders, Sexual
Interventions
DRUG

Testosterone gel

Transdermal 2% T gel applied once daily to the thighs or lower abdominal/pubic area (300 mcg T per day) for 6 months

DRUG

Estradiol ovules

Intravaginal estradiol ovules taken daily for 2 weeks and afterwards twice a week, for 6 months

DRUG

Moisturizer

Local non-hormonal moisturizers applied regularly every 2-3 days and lubricants as needed

DRUG

Testosterone gel + Estradiol ovules

Transdermal 2% T gel applied once daily to the thighs or lower abdominal/pubic area (300 mcg T per day), plus Intravaginal estradiol ovules taken daily for 2 weeks and afterwards twice a week, for 6 months

Trial Locations (1)

50136

Andrology, Women's Endocrinology and Gender Incongruence Unit, University of Florence, Azienda Ospedaliero-Universitaria Careggi, Florence

All Listed Sponsors
lead

University of Florence

OTHER

NCT04336891 - Effect of Testosterone Treatment on Clitoral Arteries' Hemodynamic Parameters. | Biotech Hunter | Biotech Hunter