2,953,748
Participants
Start Date
May 27, 2019
Primary Completion Date
March 5, 2021
Study Completion Date
March 5, 2021
Hydrochlorothiazide
Exposure to hydrochlorothiazide will be defined as a prescription for hydrochlorothiazide alone or in combination with non-ACE inhibitor antihypertensive drugs at cohort entry date.
Angiotensin-converting enzyme (ACE) inhibitors
Exposure to ACE inhibitors will be defined as a prescription for an ACE inhibitor alone or in combination with non-hydrochlorothiazide antihypertensive drugs at cohort entry date.
Centre for Clinical Epidemiology, Lady Davis Institute, Jewish General Hospital, Montreal
Drug Safety and Effectiveness Network, Canada
OTHER
Canadian Institutes of Health Research (CIHR)
OTHER_GOV
Canadian Network for Observational Drug Effect Studies, CNODES
OTHER