Evaluation of the Neuro-endocrine Response to Post-prandial Hyperinsulinaemic Hypoglycaemia.

CompletedOBSERVATIONAL
Enrollment

32

Participants

Timeline

Start Date

October 2, 2020

Primary Completion Date

July 13, 2021

Study Completion Date

July 13, 2021

Conditions
Roux-en-y Gastric BypassPost Prandial Hypoglycemia
Interventions
COMBINATION_PRODUCT

Administration of glucose and controlled induction of hypoglycaemia.

Functional metabolic test involving a 15g oral glucose load (enriched with 1.5% U-13C glucose) and subsequent controlled 20min hypoglycaemic clamp period. Neuroendocrine response will be assessed using frequent blood samples for hormones and metabolites, continuous heart rate monitoring and evaluation for hypoglycaemic symptoms.

Trial Locations (1)

3010

Department of Diabetes, Endocrinology, Nutritional Medicine and Metabolism, Bern

All Listed Sponsors
lead

Lia Bally

OTHER

NCT04334161 - Evaluation of the Neuro-endocrine Response to Post-prandial Hyperinsulinaemic Hypoglycaemia. | Biotech Hunter | Biotech Hunter