Effects of E-Cigarette Nicotine Content in Smokers (Nicotine Flux Study)

NACompletedINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

January 5, 2021

Primary Completion Date

June 1, 2023

Study Completion Date

September 8, 2023

Conditions
Electronic Cigarette Use
Interventions
OTHER

Tobacco product administration and assessment, own brand cigarettes

4 sample puffs, followed by a 60 minute rest period, hypothetical drug purchase tasks, followed by progressive ratio tasks (single product and two products, with 60 minute rest in between) where participants work to earn puffs of tobacco products; preceded and followed by physiological and subjective assessment

OTHER

Tobacco product administration and assessment, ECIG 30 Watts, 0 mg/ml nicotine

4 sample puffs, followed by a 60 minute rest period, hypothetical drug purchase tasks, followed by progressive ratio tasks (single product and two products, with 60 minute rest in between) where participants work to earn puffs of tobacco products; preceded and followed by physiological and subjective assessment

OTHER

Tobacco product administration and assessment, ECIG 30 Watts, 8 mg/ml nicotine

4 sample puffs, followed by a 60 minute rest period, hypothetical drug purchase tasks, followed by progressive ratio tasks (single product and two products, with 60 minute rest in between) where participants work to earn puffs of tobacco products; preceded and followed by physiological and subjective assessment

OTHER

Tobacco product administration and assessment, ECIG 30 Watts, 15 mg/ml nicotine

4 sample puffs, followed by a 60 minute rest period, hypothetical drug purchase tasks, followed by progressive ratio tasks (single product and two products, with 60 minute rest in between) where participants work to earn puffs of tobacco products; preceded and followed by physiological and subjective assessment

OTHER

Tobacco product administration and assessment, ECIG 30 Watts, 30 mg/ml nicotine

4 sample puffs, followed by a 60 minute rest period, hypothetical drug purchase tasks, followed by progressive ratio tasks (single product and two products, with 60 minute rest in between) where participants work to earn puffs of tobacco products; preceded and followed by physiological and subjective assessment

Trial Locations (1)

23220

Center for the Study of Tobacco Products, Richmond

All Listed Sponsors
collaborator

National Institute on Drug Abuse (NIDA)

NIH

lead

Virginia Commonwealth University

OTHER

NCT04332926 - Effects of E-Cigarette Nicotine Content in Smokers (Nicotine Flux Study) | Biotech Hunter | Biotech Hunter