NCT04332211View on ClinicalTrials.gov

Pseudoephedrine Prophylaxis for Prevention of Middle Ear Barotrauma in Hyperbaric Oxygen Therapy

PHASE4CompletedINTERVENTIONAL
Enrollment

105

Participants

Timeline

Start Date

May 1, 2021

Primary Completion Date

July 12, 2023

Study Completion Date

July 12, 2023

Conditions
Barotrauma;Ear
Interventions
PROCEDURE

Hyperbaric Oxygen Therapy

Hyperbaric oxygen therapy (HBOT) utilizes 100% oxygen delivery at a pressure greater than 1 atmosphere for the treatment of various emergent medical conditions.

DRUG

Pseudoephedrine 60 MG

administer either pseudoephedrine or placebo orally to patients requiring hyperbaric oxygen therapy

DRUG

Placebo oral tablet

administer either pseudoephedrine or placebo orally to patients requiring hyperbaric oxygen therapy

Trial Locations (1)

21201

University of Maryland Medical Center, Baltimore

All Listed Sponsors
lead

University of Maryland, Baltimore

OTHER