Ivermectin Safety in Small Children

PHASE2RecruitingINTERVENTIONAL
Enrollment

399

Participants

Timeline

Start Date

November 18, 2023

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
Scabies
Interventions
DRUG

Oral ivermectin

Ivermectin (NT007) 3 mg tablets are round, white, and scored on one side. Ivermentin 3mg tablets will be crushed and mixed thoroughly in 10mL of water.

DRUG

Permethrin Cream

permethrin cream 5% (Pioletal® Plus) is a white coloured lotion with a homogenous appearance and an odour of fennel and lavender.

OTHER

Placebo tablet

placebo tablets are round, white, scored on one side. There are no active substances in the placebo tablets.

OTHER

Placebo cream

A placebo cream is a white coloured lotion with a homogenous appearance and an odour of fennel and lavender but lacking the permethrin agent.

Trial Locations (3)

Unknown

RECRUITING

Alfredo da Matta Tropical Dermatology Foundation (FUAM), Manaus

NOT_YET_RECRUITING

Kenya Medical Research Institute, Kisumu

RECRUITING

MRC Unit The Gambia, Banjul

Sponsors
All Listed Sponsors
collaborator

Fundação Alfredo da Matta (FUAM)

UNKNOWN

collaborator

Kenya Medical Research Institute

OTHER

collaborator

Fundação de Medicina Tropical Doutor Heitor Vieira Dourado (FMT-HVD)

UNKNOWN

collaborator

Medical Research Center Unit The Gambia (MRCG)

UNKNOWN

lead

University of Oxford

OTHER