The Effect of Lumbar CSF Drainage on the Neurologic Outcome Improvement in OHCA Underwent TTM

CompletedOBSERVATIONAL
Enrollment

40

Participants

Timeline

Start Date

July 5, 2021

Primary Completion Date

April 2, 2023

Study Completion Date

January 16, 2024

Conditions
Heart Arrest, Out-Of-HospitalBrain Swelling
Interventions
PROCEDURE

lumbar CSF drainage

We have performed the lumbar CSF drainage on the level of the lumbar spine between L3 and L4 with the patient lying in the lateral decubitus position with hips and knees flexed. A lumbar drainage catheter was inserted using a HermeticTM lumbar accessory kit (Integra Neurosciences, Plainsboro, NJ, USA) in the patients. ICP monitoring via lumbar drainage catheter was practiced using the LiquoGuard® (Möller Medical GmbH \& Co KG, Fulda, Germany). ICP control strategies was initiated when ICP exceeded 15 mmHg in the absence of noxious stimuli at the rate of 10\~20 ml/h via a lumbar drainage catheter until ICP was less than 15 mmHg \[14, 15\].

Trial Locations (1)

35015

Chungnam National University Hospital, Daejeon

All Listed Sponsors
collaborator

National Research Foundation of Korea

OTHER

lead

Chungnam National University Hospital

OTHER