133
Participants
Start Date
June 3, 2020
Primary Completion Date
May 10, 2024
Study Completion Date
May 10, 2024
Lingual Muscle Stimulation
Tongue protrudor muscles will be stimulated
Mandibular advancement
Outcome variables will be assess with and without mandibular advancement
Postural maneuvers
Outcome variables will be measured with and without postural maneuvers
Digital Morphometrics
A digital camera with laser pointers will be used to capture a series of craniofacial photographs (frontal, profile and neck extended) and intra-oral photographs (junction of the hard and soft palate, airway, or base of tongue).
Tongue Force Exercise
The patient will place a small bulb behind their lower incisors and will press using their tongue as hard as possible for two seconds. This exercise will be repeated four times, with 30 seconds of rest in between each attempt. The patient will then be instructed to press and hold their tongue against the bulb as hard as possible for 35 seconds. This exercise will be repeated three times, with 2 minutes of rest in between each attempt.
Magnetic resonance imaging (MRI)
The patient will undergo an MRI scan of the head and neck.
Polysomnography (PSG) - Split Night
The patient will undergo a polysomnography (PSG). The PSG study will include monitoring of EEG, submental EMG, EOG, SpO2, tidal airflow, thoraco-abdominal efforts, and body position. The patient will spend half of the night at baseline (i.e. no intervention), and the second half with lingual muscle stimulation activated.
Hospital of the University of Pennsylvania, Philadelphia
University of Pennsylvania
OTHER