NCT04315116View on ClinicalTrials.gov

A Drug-drug Interaction Trial of Loperamide Pharmacokinetics Effect on Pyrotinib Maleate

PHASE1CompletedINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

April 13, 2020

Primary Completion Date

April 30, 2020

Study Completion Date

September 1, 2020

Conditions
Healthy Participants
Interventions
DRUG

pyrotinib maleate

a single oral dose of pyrotinib maleate on day 1 \& day10 .

DRUG

Loperamide

Loperamide 4 mg bid from day 7 to day 13

Trial Locations (1)

410008

Xiangya Hospital Central South University, Changsha

All Listed Sponsors
lead

Jiangsu HengRui Medicine Co., Ltd.

INDUSTRY

NCT04315116 - A Drug-drug Interaction Trial of Loperamide Pharmacokinetics Effect on Pyrotinib Maleate | Biotech Hunter | Biotech Hunter