NCT04314193 - Effectiveness of Methotrexate Versus Prednisone as First-line Therapy for Pulmonary Sarcoidosis | Biotech Hunter

Enrollment

138

Participants

Timeline

Start Date

June 1, 2020

Primary Completion Date

August 13, 2024

Study Completion Date

July 31, 2026

Conditions

Sarcoidosis, Pulmonary

Interventions

DRUG

Methotrexate

Oral methotrexate (15 mg weekly to be increased to 25 mg weekly) for 24 weeks.

DRUG

Prednisone

Oral prednisone (start 40 mg daily, to be tapered to 10 mg daily) for 24 weeks.

Trial Locations (17)

5223 GZ

Jeroen Bosch Ziekenhuis, 's-Hertogenbosch

1007 MB

Vrije Universiteit Medisch Centrum, Amsterdam

1061 AC

Onze Lieve Vrouwe Gasthuis, Amsterdam

1105 AZ

Academisch Medisch Centrum, Amsterdam

6815 AD

Rijnstate Ziekenhuis, Arnhem

Unknown

Amphia hospital, Breda

Catharina Ziekenhuis, Eindhoven

Medical Center Leeuwarden, Leeuwarden

VieCuri Medical Center, Venlo

7512 KZ

Medisch Spectrum Twente, Enschede

9728 NT

Martini Ziekenhuis, Groningen

6419 PC

Zuyderland Medisch Centrum, Heerlen

2333 ZA

Leids Universitair Medisch Centrum, Leiden

2262 BA

Haaglanden Medisch Centrum, Leidschendam

3425 CM

Sint Antonius Ziekenhuis, Nieuwegein

3000 CA

Erasmus MC, Rotterdam

8025 AB

Isala Klinieken, Zwolle