23
Participants
Start Date
June 4, 2020
Primary Completion Date
October 26, 2021
Study Completion Date
October 26, 2021
Glofitamab
Participants will receive intravenous (IV) glofitamab in combination with gemcitabine and oxaliplatin for up to 8 cycles, followed by up to 4 cycles of glofitamab monotherapy.
Gemcitabine
Participants will receive IV gemcitabine prior to oxaliplatin administration for up to 8 cycles.
Oxaliplatin
Participants will receive IV oxaliplatin after gemcitabine administration for up to 8 cycles.
Mosunetuzumab
Participants will receive IV mosunetuzumab in combination with gemcitabine and oxaliplatin for up to 8 cycles.
Obinutuzumab
Participants will receive a single dose of IV obinutuzumab 7 days prior to the first administration of glofitamab.
Tocilizumab
Participants will receive IV tocilizumab as needed to treat cytokine release syndrome (CRS).
Prince of Wales Hospital; Haematology, Randwick
St Vincent's Hospital Melbourne, Fitzroy
Monash Health Monash Medical Centre, Clayton
Hoffmann-La Roche
INDUSTRY