80
Participants
Start Date
May 6, 2020
Primary Completion Date
April 10, 2021
Study Completion Date
September 20, 2021
Placebo
Patients undergoing different cardiac surgical procedures will receive a continuous intravenous infusion of Normal Saline 0.9% with a starting dose of 0.0025 ml/kg/min.
Norepinephrine
Patients undergoing different cardiac surgical procedures will receive a continuous intravenous infusion of norepinephrine (40 ug/ml) with a starting dose of 0.0025 ml/kg/min.
Increase infusion rate
Infusion rate will be increased as needed in order to maintain a MAP ≥65 mmHg during cardiopulmonary bypass period as per the discretion of the anesthesiologist using 0.00125 ml/kg/min increments
Decrease infusion rate
Infusion rate will be decreased as needed in order to maintain a MAP ≥65 mmHg during cardiopulmonary bypass period as per the discretion of the anesthesiologist using 0.00125 ml/kg/min decrements
Dammam University, Khobar
Imam Abdulrahamn Bin Faisal University (Former, Dammam University), Dammam
Imam Abdulrahman Bin Faisal University
OTHER