NCT04312282View on ClinicalTrials.gov

The Effect of Tesetaxel on the QTc Interval and the Effect of Food, Itraconazole, and Rifampin on Tesetaxel Pharmacokinetics in Patients With Advanced Solid Tumors

PHASE1TerminatedINTERVENTIONAL
Enrollment

93

Participants

Timeline

Start Date

March 6, 2020

Primary Completion Date

September 30, 2020

Study Completion Date

June 15, 2021

Conditions
Advanced Solid Tumors
Interventions
DRUG

Tesetaxel

Tesetaxel orally on Day 1 of a 21-day cycle

DRUG

Tesetaxel

Tesetaxel orally on Day 1 of a 21-day cycle

DRUG

Itraconazole

Itraconazole orally once daily from Day -3 to Day 14 of a 21-day cycle

DRUG

Rifampin

Rifampin orally once daily from Day -6 to Day 14 of a 21-day cycle

Trial Locations (3)

49546

START Midwest, Grand Rapids

75320

Mary Crowley Cancer Research, Dallas

78229

NEXT Oncology, San Antonio

Sponsors
All Listed Sponsors
lead

Odonate Therapeutics, Inc.

INDUSTRY