Pro-Resolving Mediators in Acute Inflammation in Humans

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

19

Participants

Timeline

Start Date

July 2, 2018

Primary Completion Date

February 3, 2022

Study Completion Date

February 22, 2022

Conditions
Inflammation; SkinResolutionBlister
Interventions
DRUG

Lovaza

Lovaza contains ethyl esters of omega-3 fatty acids (EPA and DHA) obtained from the oil of several fish sources.

OTHER

Cantharone

Cantharone is a clinical blistering agent for topical use to remove warts and molluscum contagiosum. We plan to use the drug to elicit a small skin blister and inflammatory response. This is a well described clinical inflammation research experimental model with multiple publications of its safety and utility in tracking the host inflammatory response.

OTHER

Phlebotomy

Subjects will have blood drawn from the antecubital vein for not more than 15mL at each visit.

Trial Locations (1)

02115

Brigham and Women's Hospital, Boston

All Listed Sponsors
collaborator

National Institute of General Medical Sciences (NIGMS)

NIH

lead

Brigham and Women's Hospital

OTHER

NCT04308889 - Pro-Resolving Mediators in Acute Inflammation in Humans | Biotech Hunter | Biotech Hunter